Mastermind CORE delivers a more advanced feature set inspired by the functionality of our premium Mastermind PRO platform, applied to a curated set of clinically significant genes. This focused, powerful research tool makes variant interpretation more accessible, while serving as a gateway to the full Mastermind ecosystem.

🆓 Rotating Free Gene Access in Mastermind CORE! Each quarter we rotate a set of genes selecting them for their diagnostic relevance and aligning with awareness initiatives. This quarter’s Mastermind CORE update features 10 newly added genes covering a wide range of disorders, including sensory loss, neurodevelopmental, autoinflammatory and more – each linked to early-onset or multisystemic disease.

Ready to try Mastermind? Creating an account is free and takes seconds. Get started today.

Product Spotlight – Neurology Panel Genes now in Mastermind PRO!

We’re excited to announce the latest expansion of Mastermind’s genomic content – insights from 535 genes and over 36,000 variants commonly found in leading neurology genetic panels are now available. Curated by our expert scientific team using ACMG guidelines, these insights integrate data from gnomAD, REVEL scores, and expertly reviewed literature. This release is designed to accelerate variant interpretation, enhance diagnostic confidence, and advance research across a wide range of neurological disorders.

Watch this video to learn more!

Blog Highlights

Batten Disease Awareness Day: Advancing Hope Through Genomic Insight

Sickle Cell Awareness Day: Advancing Care Through the Power of Genetics

Undiagnosed Day: A Journey Without a Map, A Fight for Answers

Cancer Knowledgebase (CKB) Quarterly Update

🆓 Rotating Free Gene Access in CKB CORE! This quarter, Genomenon expanded the CKB CORE collection to include curated variant data on 14 key tyrosine kinase genes. Tyrosine Kinases are a well-known class of enzymes critical in signaling pathways that regulate cell growth, division and survival making them frequent drivers of cancer when mutated or overexpressed. 

Learn more about this quarter’s free genes!

Product Spotlight: Introducing the CKB Variant Navigator

We launched the CKB Variant Navigator – an intuitive tool for visualizing protein variants and identifying functional and resistance hotspots. Designed for fast clinical and therapeutic relevance, this new feature empowers users to explore the impact of specific mutations in real time.

Explore how this tool helps you move from investigation and insight to action with greater confidence.

Blog Highlights

Decoding Solid Tumors: How CKB Powers Precision Oncology with Genomic Intelligence

The Genetic Code Beneath the Surface: Uncovering Melanoma’s Molecular Blueprint

Genomic Intelligence in Brain Cancer: From Curated Insights to Targeted Treatments

Meet our team and discover how we’re enabling clinical teams to interpret more variants in less time – without sacrificing accuracy.

Stop by our booth to see how we’re transforming somatic variant interpretation with curated insights that support precision oncology and clinical decision-making.

NEWS & ANNOUNCEMENTS

Genomenon Powers Groundbreaking Study on Genetic Drivers of Rare Liver Disorders

Intelliseq Integrates Genomenon’s Cancer Knowledgebase (CKB) into iFlow Platform to Advance Somatic Variant Interpretation 

Need variant clarity? Let’s talk.
Whether you’re focused on rare disease, oncology, or clinical interpretation at scale, Genomenon’s team is ready to help.